WebApr 26, 2024 · Currently, pharmaceutical companies are working on innovative methods, processes and products. Oral mucoadhesive systems, such as tablets, gels, and polymer films, are among these possible products. Oral mucoadhesive systems possess many advantages, including the possibility to be applied in swallow … WebNov 3, 2024 · The nanofibrous matrix was observed to be more mucoadhesive than a film. 10 Tyagi et al prepared mucoadhesive PVA nanofibers associated with PVA/HPMC backing layer, in this research the mucoadhesive fibers were loaded with diphenhydramine, which showed an average disintegration time of 7–60 seconds, the system presented 42%–82% …
Marketed oral mucoadhesive drug delivery systems
WebOct 15, 2015 · For mucoadhesive oral films (MOF) it is necessary to include polymers that exhibit good adhesive properties to mucosal membranes (e.g., cellulose derivates, … WebJul 23, 2014 · Oral mucosa is an attractive region for the local and systemic application of many drugs. Oral mucoadhesive films are preferred for their prolonged time of residence, the improved... how many grams equal a milliliter
Development of mucoadhesive buccal films for the treatment of …
WebNov 6, 2024 · In general, buccal films are seen as a promising alternative application route for drugs as they combine several features, like better patient compliance (no swallowing and the possibility to modify the taste) and increased bioavailability (reviewed in 12). We developed a novel MTK oral mucoadhesive film to circumvent the limitations of MTK in its WebThe films were evaluated in terms of thickness, weight, folding endurance, surface pH, drug content, swelling, mucoadhesive properties, release characteristics, and in vivo anti … WebDec 23, 2024 · Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice . Authors Johanna Michael 1 , Diana Bessa de Sousa 1 , Justin Conway 2 , Erick Gonzalez-Labrada 2 , Rodolphe Obeid 2 , Julia Tevini 3 , Thomas Felder 3 , Birgit Hutter-Paier 4 , Horst Zerbe 2 , Nadine Paiement 2 , Ludwig Aigner 1 4 5 Affiliations hover effect on links css