Hif 1 alpha uniprot

WebProduct Specific Information. MA1-516 detects hypoxia-inducible factor 1 alpha (HIF-1 alpha) from human, non-human primate, bovine, mouse and porcine cells. This antibody does not cross-react with ARNT or the related HIF-2 alpha. MA1-516 has been successfully used in Western blot, immunofluorescence, immunoprecipitation, immunocytochemistry ... WebWe investigated the impact of inhibiting HIF-1α transcriptional activity on cytotoxic immune cell infiltration into B16-F10 melanoma. We showed that tumors expressing a deleted form of HIF-1α displayed increased levels of NK and CD8 + effector T cells in the tumor microenvironment, which was associated with high levels of CCL2 and CCL5 ...

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WebResearch Information. HIF-1α Antibody (28b) is an IgG κ mouse monoclonal HIF-1 alpha antibody (also designated HIF1A antibody or HIF-1 alpha antibody) suitable for the … WebBackground: HIF-1 alpha/HIF1A. This biotinylated peptide includes a sequence from human Hypoxia-Inducible Factor 1-alpha (HIF-1 alpha ) including a 4-hydroxyline proline … literacy adapted dash diet https://naughtiandnyce.com

RCSB PDB - 1H2K: Factor Inhibiting HIF-1 alpha in complex with …

Web21 de mar. de 2024 · HIF1A (Hypoxia Inducible Factor 1 Subunit Alpha) is a Protein Coding gene. Diseases associated with HIF1A include Retinal Ischemia and Enchondromatosis, Multiple, Ollier Type.Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated degradation.Gene … WebCharacterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins. Biochem Biophys Res Commun 260, 557-561. Tanimoto, K., Makino, Y., Pereira, T., and Poellinger, L. (2000). Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein. literacy adventures

RCSB PDB - 3KCY: Factor inhibiting HIF-1 alpha in complex with 8 ...

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Hif 1 alpha uniprot

HIF-1 alpha Antibody , Abways Technology

WebMonoclonal Anti-HIF2 alpha antibody produced in mouse. clone GT125, affinity isolated ... UniProt accession no. Q16665. shipped in. wet ice. storage temp. −20°C. Gene ... Hif1a(15251) rat ... Hif1a(29560) Description. General description. Hypoxia-inducible factor-1 (HIF-1) is a 120kD basic helix-loop-helix protein that belongs to the PAS ... Web2 de fev. de 2024 · The enrichment pathways identified following KEGG analysis that contained the most core targets (p < 0.05) included cocaine addiction, calcium signaling pathway, arginine biosynthesis, HIF-1 signaling pathway, pathways of neurodegeneration-multiple diseases, estrogen signaling pathway, chemical carcinogenesis-receptor …

Hif 1 alpha uniprot

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Web12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent … Web19 de mar. de 2002 · Disruption of the Hif-1 alpha/p300 interaction has been linked to attenuation of tumor growth. To delineate the structural basis for this interaction, ...

Web9 de mai. de 2002 · Crystal structure of a hydroxylated HIF-1 alpha peptide bound to the pVHL/elongin-C/elongin-B complex. ... Hypoxia-inducible factor 1 ALPHA: D: 34: N/A: Mutation(s): 1 : UniProt & NIH Common Fund Data Resources: Find proteins for Q16665 (Homo sapiens) Explore Q16665 . Go to UniProtKB: Q16665. PHAROS: Q16665. WebUniProt : Q16665; Isotype : Rabbit IgG Clonality : Monoclonal; Price : $185/50μl, $299/100μl Availability : Ship next day Rank: Download datasheet [PDF] : Category. Primary Antibodies; ... HIF-1 alpha Antibody detects endogenous levels of total HIF-1 …

Web17 de jan. de 2003 · The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent hydroxylation. Under normoxic conditions, hydroxylation … WebHIF-1 alpha in vitro CatchPoint ® SimpleStep ELISA ® (Enzyme-Linked Immunosorbent Assay) kit is designed for the quantitative measurement of HIF1a protein in human cell extracts. This CatchPoint SimpleStep ELISA kit has been optimized for Molecular Devices Microplate Readers. Click here for a list of recommended Microplate Readers.

Web6 de out. de 2024 · HIF is a transcription factor that plays an essential role in the cellular response to low oxygen, orchestrating a metabolic switch that allows cells to survive in this environment. In immunity, infected and inflamed tissues are often hypoxic, and HIF helps immune cells adapt. HIF-α stabilization ca …

WebIn HeLa cells, the levels of HIF-1 alpha and HIF-1 beta protein and HIF-1 DNA-binding activity increased exponentially as cellular oxygen tension decreased, with maximum values at 0.5% oxygen and half-maximal values at 1.5 to 2% oxygen. HIF-1 alpha and HIF-1 beta (ARNT) mRNAs were detected in all human, mouse, and rat organs assayed and mRNA ... literacy adjective formWeb結構. 缺氧大部分需要氧氣呼吸的物種,都擁有保守序列HIF-1。 其轉錄都有嚴格的調控機制。HIF-1是由一個α亞基和一個β亞基組成的異源蛋白二聚體,而β亞基是一種 芳香烃受体核转位子 ( 英语 : Aryl hydrocarbon receptor nuclear translocator ) (ARNT) 。 HIF-1屬於鹼性螺旋-環-螺旋(bHLH)家族中的PER-ARNT-SIM ... implementasi internet of thingsWebBackground: HIF-1 alpha/HIF1A. This biotinylated peptide includes a sequence from human Hypoxia-Inducible Factor 1-alpha (HIF-1 alpha ) with an unmodified (non-hydroxylated) proline residue corresponding to proline 564 in UniProt Q16665. The peptide is not efficiently ubiquitinated by a VHL/Elongin B/Elongin C/CUL2/RBX complex (catalog … literacy adult and community education systemWeb27 de fev. de 2024 · UniProt Q16665 - HIF1A_HUMAN. Gene HIF1A Modification Unmodified View Product On Supplier's Website Request a Quote ... HIF1, BHLHE78, MOP1, PASD8, HIF-1A, HIF-1alpha, HIF1-ALPHA, HIF-1-alpha. View additional product information. Experiments from the literature. Loading published images for this product … implement a stack using singly linked listWeb12 de ago. de 2002 · 1H2K, 1H2L, 1H2M, 1H2N. PubMed Abstract: The activity of the transcription factor hypoxia-inducible factor (HIF) is regulated by oxygen-dependent … implement a soar with customizable playbooksWeb29 de fev. de 2004 · Hypoxia-inducible factor (HIF-1) is an oxygen-dependent transcriptional activator, which plays crucial roles in the angiogenesis of tumors and mammalian development. HIF-1 consists of a constitutively expressed HIF-1beta subunit and one of three subunits (HIF-1alpha, HIF-2alpha or HIF-3alpha). The s … literacy advancementWebUniProt Q16665 - HIF1A_HUMAN. Gene HIF1A Modification Unmodified View Product On Supplier's Website Request a Quote ... HIF1, BHLHE78, MOP1, PASD8, HIF-1A, HIF-1alpha, HIF1-ALPHA, HIF-1-alpha. View additional product information. Experiments from the literature. Loading published images for this product Validations. None available. … literacy advance